Kerala, India, is grappling with a resurgence of the Nipah virus in 2025, with four confirmed cases — including two fatalities — reported within a 50-kilometer radius spanning Malappuram and Palakkad districts. The most recent case, confirmed on July 12, involved a 52-year-old man in Palakkad. This marks the tenth Nipah virus spillover in Kerala since 2018.
Currently, 675 individuals are under surveillance across five districts. Authorities are escalating containment efforts to prevent further spread of this deadly zoonotic virus.
The Nipah virus is primarily transmitted from fruit bats to humans and causes severe symptoms like fever, headache, respiratory distress, and encephalitis. It has a mortality rate ranging from 40% to 75%. While human-to-human transmission is rare, it has occurred in hospital settings during past outbreaks. Kerala’s 2018 outbreak claimed 17 lives, highlighting the virus’s deadly potential. Fortunately, the current cases appear to be isolated spillovers with no secondary transmission reported yet.
The state’s health department has responded rapidly. Contact tracing is underway, with 571 contacts currently being monitored in Malappuram, Palakkad, and Kozhikode. Containment zones have been established, enforcing movement restrictions and mask mandates. Schools and public transport in high-risk zones have also been temporarily shut.
Kerala now has four advanced laboratories conducting RT-PCR tests for Nipah, enabling faster diagnosis. Though no specific treatment or vaccine exists, doctors are using broad-spectrum antivirals like Ribavirin and Remdesivir to manage symptoms.
Experts attribute recurring outbreaks in Kerala to its dense fruit bat population and seasonal ecological factors, especially monsoon-driven human-bat interactions. While the exact source of the current outbreak remains unclear, officials are testing bat habitats for the virus and enhancing surveillance for acute encephalitis and respiratory symptoms.
Health officials continue to stress a “One Health” approach, integrating human, animal, and environmental monitoring to better predict and prevent future spillovers.
Despite the recurring threats, Kerala’s prompt interventions and public health infrastructure have helped limit the virus’s spread so far. But with the virus still present in local bat populations, the risk remains — demanding sustained awareness and preparedness across the state.
Published in SouthAsianDesk, July 26th, 2025
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